Knobeloch L M, Ziarnik M, Anderson H A, Dodson V N
Wisconsin Bureau of Public Health, Department of Health and Social Services, Madison 53703, USA.
Environ Health Perspect. 1995 Jun;103(6):604-6. doi: 10.1289/ehp.95103604.
The Wisconsin Division of Health investigated mercury exposure in a 40-year-old man, his 42-year-old wife, and their 2.5-year-old son. At the time of our investigation, these individuals had blood mercury levels ranging from 37 to 58 micrograms/L (normal < 5 micrograms/L) and hair samples from the adults contained 10-12 micrograms mercury/g dry weight. A personal interview and home inspection failed to identify any occupational or household sources of mercury exposure. The family's diet included three to four fish meals per week. The fish was purchased from a local market and included Lake Superior whitefish, Lake Superior trout, farm-raised trout and salmon, and imported seabass. Analysis of these fish found that only one species, the imported seabass, contained significant mercury levels. Two samples of the seabass obtained from the vendor on different days contained mercury concentrations of 0.5 and 0.7 mg/kg. Based on consumption estimates, the average daily mercury intakes for these individuals ranged from 0.5 to 0.8 micrograms/kg body weight. Six months after the family stopped consuming the seabass, blood mercury levels in this man and woman were 5 and 3 micrograms/L, respectively. Analysis of sequential blood samples confirmed that mercury elimination followed first-order kinetics with a half-life of approximately 60 days.
威斯康星州卫生部门对一名40岁男子、他42岁的妻子及其2.5岁的儿子的汞暴露情况进行了调查。在我们调查时,这些人的血液汞含量在37至58微克/升之间(正常水平<5微克/升),成年人的头发样本中汞含量为10 - 12微克汞/克干重。通过个人访谈和家庭检查,未发现任何职业或家庭汞暴露源。这家人的饮食每周包括三到四顿鱼餐。这些鱼是从当地市场购买的,包括苏必利尔湖白鱼、苏必利尔湖鳟鱼、养殖鳟鱼和鲑鱼以及进口海鲈鱼。对这些鱼的分析发现,只有一种鱼,即进口海鲈鱼,汞含量较高。从供应商处不同日期获取的两份海鲈鱼样本汞浓度分别为0.5和0.7毫克/千克。根据摄入量估计,这些人的平均每日汞摄入量为0.5至0.8微克/千克体重。这家人停止食用海鲈鱼六个月后,该男子和女子的血液汞含量分别为5微克/升和3微克/升。对连续血液样本的分析证实,汞的消除遵循一级动力学,半衰期约为60天。