Gerigk M, Glanzmann R, Rascher W, Gnehm H E
Zentrum für Kinderheilkunde, Giessen, Germany.
Eur J Pediatr. 1995 Jul;154(7):582-4. doi: 10.1007/BF02074840.
Three children with severe hyponatraemia and hyperkalaemia associated with acute pyelonephritis are reported. All were very young male infants in a poor general condition and seriously dehydrated. Diagnostic procedures did not detect obstructive uropathy or vesico-ureteric reflux.
Hyponatraemia and hyperkalaemia occurs in young infants with severe acute pyelonephritis in the absence of obstructive uropathy or vesico-ureteric reflux. The severe inflammation of the kidney itself may explain the electrolyte disturbance by a transient resistance of the distal tubule to aldosterone.
