Morelli S, De Castro S, Cartoni D, Perrone C, Beni S, Bernardo M L, Ferrante L, Giordano M
Istituto Di I Clinica Medica, Università La Sapienza, Roma.
G Ital Cardiol. 1995 Jul;25(7):851-7.
The simple determination of transaortic pressure gradient does not accurately assess the severity of an aortic valve stenosis. Thus, estimating the aortic valve area (AVA) is vital for clinical decision-making. Cardiac catheterization has been considered the "gold-standard" for the quantification of the stenotic valve area, but this technique may underestimate the actual valve area when aortic regurgitation is associated. Doppler transthoracic echocardiography (TTE) with the continuity equation method is usually employed for AVA estimation. Recently, in pure aortic stenosis, transesophageal echocardiography (TEE) has provided AVA values well-correlated to hemodynamic invasive results.
In this study, we correlated AVA values by TTE and multiplane TEE in 18 patients with combined aortic valve stenosis and regurgitation.
The mean values of AVA by TEE and TTE were 0.74 +/- 0.12 and 0.68 +/- 0.55 cm2, respectively (p = NS). TEE-derived AVA correlated well to TTE-derived AVA (r = 0.816; p < 0.0001). Critical aortic stenosis was predicted by TEE with 100% sensitivity and specificity. Total time of examination was significantly longer for TTE (p < 0.00001).
In conclusion, direct planimetry by multiplane TEE is a reliable method for AVA determination in aortic stenoinsufficiency. For this purpose, when the technical quality of TTE study is poor or when the patient is critically ill and does not tolerate a longer lasting TTE, multiplane TEE should be considered.
单纯测定跨主动脉压力阶差并不能准确评估主动脉瓣狭窄的严重程度。因此,估算主动脉瓣面积(AVA)对于临床决策至关重要。心导管检查一直被视为量化狭窄瓣膜面积的“金标准”,但当合并主动脉反流时,该技术可能会低估实际瓣膜面积。采用连续方程法的经胸多普勒超声心动图(TTE)通常用于AVA估算。最近,在单纯主动脉狭窄中,经食管超声心动图(TEE)所提供的AVA值与血流动力学侵入性检查结果具有良好的相关性。
在本研究中,我们对18例合并主动脉瓣狭窄和反流患者的TTE和多平面TEE所测AVA值进行了相关性分析。
TEE和TTE所测AVA的平均值分别为0.74±0.12和0.68±0.55cm²(p=无显著性差异)。TEE所测AVA与TTE所测AVA具有良好的相关性(r=0.816;p<0.0001)。TEE预测重度主动脉狭窄的敏感性和特异性均为100%。TTE的总检查时间明显更长(p<0.00001)。
总之,多平面TEE直接测量法是测定主动脉狭窄伴反流患者AVA的可靠方法。为此,当TTE检查的技术质量较差或患者病情危重且无法耐受长时间的TTE检查时,应考虑采用多平面TEE。