Kohn S, Fradis M, Podoshin L, Ben-David Y, Zidan J, Robinson E
Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
Harefuah. 1995 Jun 15;128(12):767-8, 823.
The ultrastructural effects of gentamicin on the stria vascularis of the inner ear of guinea pigs were studied by transmission electron microscopy. In a single specimen of an isolated, inner ear we found an unexpected variation in the structure of the stria vascularis in a normal, pigmented, guinea pig not treated with ototoxic drugs. There were prominent, wide protrusions from the apical surfaces of marginal cells into the endolymphatic space. This finding has not been previously reported and was seen in only 1 of 7 animals studied. It may be considered a normal structural variation, and is not pathological change in the stria vascularis due to ototoxic drugs.
通过透射电子显微镜研究了庆大霉素对豚鼠内耳血管纹的超微结构影响。在一个分离的内耳标本中，我们在一只未用耳毒性药物处理的正常、有色豚鼠的血管纹结构中发现了意外变化。边缘细胞的顶端表面有明显、宽阔的突起伸入内淋巴间隙。这一发现此前未见报道，且仅在7只研究动物中的1只身上观察到。它可能被视为一种正常的结构变异，而非耳毒性药物导致的血管纹病理变化。
