Verzijl J M, Wierckx F C, van Dijk A, Savelkoul T J, Glerum J H
Department of Pharmacy, Central Military Hospital, Ministry of Defence, Utrecht, The Netherlands.
Health Phys. 1995 Oct;69(4):543-8. doi: 10.1097/00004032-199510000-00014.
Radiocesium may be deposited in the environment as a result of accidents in nuclear installations, for example, as in Chernobyl. Significant internal contamination with radiocesium poses a serious risk to human health, and, therefore, expedient removal is essential to reduce the radiation body burden. In vitro hemodialysis was tested as a potential method to remove radiocesium from a pasteurized plasma solution of bovine or human blood. Clearance values were calculated by a flow independent method. Hemodialysis appears to be a good method to remove radiocesium from blood: within 4 h more than 90% of the administered radiocesium is removed from blood or plasma. Radiocesium in dialysis fluid can be concentrated on Prussian Blue coated columns that were tested previously for hemoperfusion. Radioactive waste disposal problems can be solved by concentration of radiocesium on these columns. In vivo experiments are necessary to confirm these in vitro results.
放射性铯可能因核设施事故而沉积在环境中，例如像切尔诺贝利事故那样。放射性铯的大量体内污染对人类健康构成严重风险，因此，为降低身体的辐射负担，及时清除至关重要。体外血液透析作为一种从牛血或人血的巴氏消毒血浆溶液中去除放射性铯的潜在方法进行了测试。清除率值通过一种与流量无关的方法计算得出。血液透析似乎是从血液中去除放射性铯的一种好方法：在4小时内，超过90%注入的放射性铯可从血液或血浆中去除。透析液中的放射性铯可浓缩在先前用于血液灌流测试的普鲁士蓝涂层柱上。通过在这些柱上浓缩放射性铯可解决放射性废物处置问题。需要进行体内实验来证实这些体外实验结果。
