Rosso R, Gianelli U, Carnevali L
Department of Human Pathology, University of Pavia, Italy.
J Cutan Pathol. 1995 Apr;22(2):164-7. doi: 10.1111/j.1600-0560.1995.tb01401.x.
A case of a vascular tumor clinically and pathologically consistent with acquired progressive lymphangioma (benign lymphangioendothelioma) in a 48-year-old woman is reported. The lesion appeared in the skin close to a mastectomy scar 3 years after surgery and radiotherapy for invasive ductal carcinoma. On histologic examination, it mimicked an aggressive vascular neoplasm because of its infiltrative pattern. However, follow-up studies confirmed the benign nature of the lesion, clinically and histologically. This case indicates that acquired progressive lymphangioma may follow radiotherapy and must be considered in the differential diagnosis of other vascular proliferations occurring in the skin of the breast, especially of low-grade postradiation angiosarcoma, a recently described neoplastic entity.
报告了一例48岁女性的血管肿瘤病例，该病例在临床和病理上与获得性进行性淋巴管瘤（良性淋巴管内皮瘤）相符。病变出现在侵袭性导管癌手术和放疗3年后乳房切除瘢痕附近的皮肤。组织学检查时，因其浸润性生长模式，该病变类似侵袭性血管肿瘤。然而，随访研究在临床和组织学上均证实了该病变的良性性质。该病例表明，获得性进行性淋巴管瘤可能发生在放疗后，在鉴别诊断乳房皮肤出现的其他血管增殖性病变时，尤其是低度放射性血管肉瘤（一种最近描述的肿瘤实体）时，必须考虑到这一情况。
