A double blind crossover comparison of high and low sodium dialysis.

A single high sodium dialysis results in a rise in serum sodium that osmotically parallels the fall in BUN. Effective net weight loss is accompanied by strikingly fewer disequilibrium symptoms, fewer muscle cramps, and less hypotension during high sodium dialysis compared to standard, hyponatric dialysis. Fewer muscle cramps during the following interdialytic interval and no increase in blood pressure or weight gain during the following interdialytic interval occurs with high sodium dialysis.