Achenbach H, Hübner H, Vierling W, Brandt W, Reiter M
Institut für Pharmazie und Lebensmittelchemie der Universität Erlangen, Germany.
J Nat Prod. 1995 Jul;58(7):1092-6. doi: 10.1021/np50121a019.
Spiganthine [1] was isolated as the main cardioactive principle from medicinally used extracts of Spigelia anthelmia. Its structure was established by spectroscopic methods. The biological effect of spiganthine is characterized by a delay in contraction development of the heart muscle.