Dubovsky S L, Thomas M
Department of Psychiatry, University of Colorado School of Medicine, Denver, USA.
J Psychosom Res. 1995 May;39(4):429-44. doi: 10.1016/0022-3999(94)00043-5.
Serotonin is a ubiquitous neurotransmitter with widespread projections that provide for the involvement of serotonin in the regulation of many biological and psychological functions. A variety of serotonin receptor subtypes exist that mediate overlapping psychobiological functions and that are targets for a new generation of medications. Although these new generation medications appear to possess great biochemical specificity, their actions extend to many psychiatric disorders, reflecting the many interactions of serotonergic subsystems.
血清素是一种广泛存在的神经递质,其投射广泛,使得血清素参与到许多生物和心理功能的调节中。存在多种血清素受体亚型,它们介导重叠的心理生物学功能,并且是新一代药物的作用靶点。尽管这些新一代药物似乎具有很高的生化特异性,但其作用涉及多种精神障碍,这反映了血清素能子系统的诸多相互作用。