Graver V, Ljunggren A E, Malt U F, Loeb M, Haaland A K, Magnaes B, Lie H
Department of Neurology, Ullevaal University Hospital, Oslo, Norway.
J Psychosom Res. 1995 May;39(4):465-76. doi: 10.1016/0022-3999(94)00148-x.
In a prospective study 122 patients with herniated lumbar disc pre-operatively completed psychological questionnaires. Surgical outcome was evaluated 12 months post-operatively mainly by a composite clinical overall score (COS), and by its separate elements. Anxiety (HAD-A scale) and psychosomatic symptoms (MSPQ) had predictive value: fewer symptoms favoured a satisfactory overall outcome, and vice versa. The HAD-A Scale had a predictive power of poor (ppp) and satisfactory (pps) outcome of 28 and 81%, respectively. Correspondingly, for the MSPQ, the ppp and pps were 42 and 85%. Anamnestic and biological variables (including fibrinolytic variables: ECLT and PAI-1) predicted 20% of the outcome. By adding all psychological variables the prediction increased only to 24%, but the HAD-A Scale and the MSPQ were still significant. The results suggest that in order to further improve prediction of outcome, future studies should combine biological variables sensitive to the mental state of the patient, with psychometric assessments.
在一项前瞻性研究中,122例腰椎间盘突出症患者术前完成了心理问卷。术后12个月主要通过综合临床总体评分(COS)及其各个组成部分对手术结果进行评估。焦虑(医院焦虑抑郁量表-焦虑分量表[HAD-A量表])和心身症状(多维症状问卷[MSPQ])具有预测价值:症状越少,总体结果越令人满意,反之亦然。HAD-A量表对不良(ppp)和满意(pps)结果的预测能力分别为28%和81%。相应地,对于MSPQ,ppp和pps分别为42%和85%。既往史和生物学变量(包括纤溶变量:优球蛋白溶解时间[ECLT]和纤溶酶原激活物抑制剂-1[PAI-1])可预测20%的结果。通过加入所有心理变量,预测率仅提高到24%,但HAD-A量表和MSPQ仍然具有显著性。结果表明,为了进一步提高对结果的预测,未来的研究应将对患者心理状态敏感的生物学变量与心理测量评估相结合。