Puttick M P, Stein H B, Chan R M, Elwood R K, How A R, Reid G D
Department of Medicine, University of British Columbia, British Columbia Centre for Disease Control (TB Division), Vancouver, Canada.
J Rheumatol. 1995 Jul;22(7):1321-5.
To describe the clinical characteristics of soft tissue tuberculosis (TB).
Retrospective review of all cases of soft tissue TB seen by the authors.
Eleven cases were seen between 1988 and 1994. All patients but one were foreign born. Six patients had collagen vascular disorders and another had a kidney transplant. Five were taking immunosuppressive therapy and/or prednisone. Three had preceding trauma to the affected area. Five had evidence of previous TB by history or chest radiograph. Symptoms (mean duration 4.4 months) included swelling and pain and often mimicked the underlying disease. Six patients had definite or suspected active TB at other sites. Good initial responses were seen with debridement or drainage and multiple drugs for 6 to 12 months. Two patients have had possible relapses at other sites. Medication intolerance was frequent.
TB should be considered in patients who present with unexplained soft tissue swelling and pain, particularly if they are immunosuppressed, were foreign born in an endemic area, have an abnormal chest radiograph, or have had trauma to the affected area.
描述软组织结核（TB）的临床特征。
对作者诊治的所有软组织结核病例进行回顾性分析。
1988年至1994年间共诊治11例。除1例患者外，其余均为外国出生。6例患者患有胶原血管疾病，另1例接受过肾移植。5例正在接受免疫抑制治疗和/或使用泼尼松。3例在患区有先前的创伤史。5例根据病史或胸部X线片有既往结核证据。症状（平均持续时间4.4个月）包括肿胀和疼痛，常与潜在疾病相似。6例患者在其他部位有明确或疑似活动性结核。清创或引流并联合多种药物治疗6至12个月后，初期反应良好。2例患者在其他部位可能复发。药物不耐受情况常见。
对于出现不明原因软组织肿胀和疼痛的患者，尤其是免疫抑制患者、在结核病流行地区出生的外国人、胸部X线片异常或患区有创伤史的患者，应考虑结核病。
