精索静脉曲张切除术对患有精索静脉曲张的不育男性血清睾酮水平的影响。
The effect of varicocelectomy on serum testosterone levels in infertile men with varicoceles.
作者信息
Su L M, Goldstein M, Schlegel P N
机构信息
James Buchanan Brady Foundation, Department of Urology, New York Hospital-Cornell Medical Center, New York, USA.
出版信息
J Urol. 1995 Nov;154(5):1752-5.
PURPOSE
We evaluated the effect of varicocelectomy on serum testosterone.
MATERIALS AND METHODS
We retrospectively reviewed the effect of varicocelectomy on serum testosterone levels in 53 infertile men with varicoceles.
RESULTS
Mean serum testosterone increased from a preoperative level of 319 +/- 12 to 409 +/- 23 ng./dl. postoperatively (p < 0.0004). Men with at least 1 firm testis preoperatively had a greater increase in serum testosterone (p < 0.005). An inverse correlation was noted between preoperative testosterone levels and change in testosterone after varicocelectomy (r = -0.34, p < 0.013).
CONCLUSIONS
Varicocelectomy can increase serum testosterone for infertile men with varicoceles. Although improvement in serum testosterone does not necessarily cause a direct improvement in semen quality, varicocelectomy may improve hormonal and spermatogenic function.
目的
我们评估了精索静脉曲张切除术对血清睾酮的影响。
材料与方法
我们回顾性分析了精索静脉曲张切除术对53例患有精索静脉曲张的不育男性血清睾酮水平的影响。
结果
血清睾酮均值从术前的319±12 ng./dl升至术后的409±23 ng./dl（p < 0.0004）。术前至少有一侧睾丸质地坚实的男性血清睾酮升高更为明显（p < 0.005）。术前睾酮水平与精索静脉曲张切除术后睾酮变化之间呈负相关（r = -0.34，p < 0.013）。
结论
精索静脉曲张切除术可提高患有精索静脉曲张的不育男性的血清睾酮水平。虽然血清睾酮水平的改善不一定会直接改善精液质量，但精索静脉曲张切除术可能会改善激素和生精功能。
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