Fisher A M, Murphree A L, Gomer C J
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027, USA.
Lasers Surg Med. 1995;17(1):2-31. doi: 10.1002/lsm.1900170103.
Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed.
光动力疗法（PDT）是一种治疗方式，它利用一种由激光产生的光激活的光敏药物，并且已被证明在肿瘤学和非肿瘤学应用中有效。本报告概述了光动力疗法中涉及的光敏剂、光化学、光生物学以及激光。对涉及卟吩姆钠和各种第二代光敏剂的临床和临床前光动力疗法研究进行了综述。
