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[表现为痛风的慢性粒细胞白血病。关于黑非洲继发性痛风的思考]

[Chronic myeloid leukemia manifesting as gout. Reflections on secondary gout in Black Africa].

作者信息

Mijiyawa M, Segbena A, David M

机构信息

Service de Rhumatologie, Centre Hospitalier Universitaire Tokoin, Lomé, Togo.

出版信息

Med Trop (Mars). 1995;55(2):154-6.

PMID:7564998
Abstract

This report describes the case of a 63-year-old obese and alcoholic butcher who suffered two episodes of distal oligoarthritis. These episodes were attributed to gout on the basis of response to colchicine and demonstration of hyperuricemia. Given the presence of hepatomegaly, splenomegaly and hyperleukocytosis, a sternal puncture and myelogram were performed and led to diagnosis of chronic myelogenous leukemia. In addition to the classic predisposing factors for gout, sickle cell anemia could be implicated in Black Africa. Longer life expectancy for patients with sickle cell anemia could increase the incidence of gout in Black Africa.

摘要

本报告描述了一名63岁肥胖且酗酒的屠夫的病例,他曾两次发作远端少关节炎。基于对秋水仙碱的反应及高尿酸血症的证实,这些发作被归因于痛风。鉴于存在肝肿大、脾肿大和白细胞增多,进行了胸骨穿刺和骨髓造影,结果诊断为慢性粒细胞白血病。除了痛风的典型诱发因素外,镰状细胞贫血在非洲黑人中也可能与之相关。镰状细胞贫血患者预期寿命的延长可能会增加非洲黑人痛风的发病率。

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