Lim C T, Koh M T, Sivanesaratnam V
Department of Paediatrics, University Hospital, Kuala Lumpur.
Med J Malaysia. 1995 Jun;50(2):131-5.
Between February 1990 and May 1993, 13 cases of early congenital syphilis (ECS) were managed in the Paediatrics Unit, University Hospital, Kuala Lumpur. Twelve mothers were unbooked with 10 inborn babies. Only one mother had antenatal booking at this hospital but she defaulted antenatal follow-up. Several risk factors associated with ECS were identified: inadequate or no prenatal care (5/13), failure to repeat a serological test for syphilis in the third trimester when it was tested negative at first booking (5/13), sexual promiscuity, substance abuse and a past history of contracting sexually transmitted disease. All 10 mothers who had their serological test repeated at delivery were found to have a positive VDRL and TPHA. Adequate antenatal care early referral of infected, expectant mothers for treatment, and a repeat serological test for syphilis could have prevented these cases of ECS.
1990年2月至1993年5月期间，吉隆坡大学医院儿科病房收治了13例早期先天性梅毒（ECS）病例。12名母亲未进行产前登记，其中10名婴儿为顺产。只有一名母亲在该医院进行了产前登记，但她未按要求进行产前随访。已确定了一些与早期先天性梅毒相关的危险因素：产前护理不足或未进行产前护理（5/13）、首次产前检查梅毒血清学检测呈阴性但在孕晚期未重复进行梅毒血清学检测（5/13）、性滥交、药物滥用以及既往有性传播疾病感染史。所有10名在分娩时重复进行血清学检测的母亲均被发现VDRL和TPHA呈阳性。充分的产前护理、对感染的孕妇尽早转诊治疗以及重复进行梅毒血清学检测本可预防这些早期先天性梅毒病例。
