Richardson G A, Day N L, Goldschmidt L
University of Pittsburgh School of Medicine, Western Psychiatric Institute & Clinic, PA 15213, USA.
Neurotoxicol Teratol. 1995 Jul-Aug;17(4):479-87. doi: 10.1016/0892-0362(95)00006-d.
These data are from a longitudinal study of prenatal alcohol and marijuana use in a low income sample. Half of the women were black and half were white. Women who used alcohol and/or marijuana during their pregnancies were light to moderate users; most decreased or discontinued their use after the first trimester. At the first follow-up phase, which occurred at a median age of 9 months, the children were functioning above average on the Bayley Scales of Infant Development (BSID). Prenatal alcohol and tobacco use did not predict BSID mental or motor scores at this phase. Third trimester marijuana use was associated with decreased BSID mental scores. Age at assessment was the most important predictor at this phase. The second follow-up occurred at a median age of 19 months when the group means for the BSID were lower. Prenatal alcohol and marijuana use did not predict outcome at this phase. Prenatal and current cigarette use were associated with decreased BSID mental scores. Demographic and environmental variables were important predictors at this phase.
这些数据来自一项针对低收入样本中孕期酒精和大麻使用情况的纵向研究。一半的女性为黑人,另一半为白人。孕期使用酒精和/或大麻的女性属于轻度至中度使用者;大多数人在孕早期过后减少或停止了使用。在第一次随访阶段,即中位年龄为9个月时,这些儿童在贝利婴儿发育量表(BSID)上的表现高于平均水平。孕期酒精和烟草使用并不能预测该阶段的BSID智力或运动得分。孕晚期使用大麻与BSID智力得分降低有关。评估时的年龄是该阶段最重要的预测因素。第二次随访在中位年龄19个月时进行,此时BSID的组均值较低。孕期酒精和大麻使用并不能预测该阶段的结果。孕期和当前吸烟与BSID智力得分降低有关。人口统计学和环境变量是该阶段的重要预测因素。