Tranchant C, Bhatia K P, Marsden C D
University Department of Neurology, Institute of Neurology, London, UK.
Mov Disord. 1995 Jul;10(4):418-23. doi: 10.1002/mds.870100403.
Movement disorders (MD), other than tremor, associated with multiple sclerosis (MS) occur infrequently. We report 14 new cases of whom nine had dystonia, three parkinsonism, and two had myoclonus. We also reviewed 135 such cases from the literature. From an analysis of the individual MDs and the site of the lesions described, we conclude that paroxysmal dystonias (tonic spasms), ballism/chorea, and palatal myoclonus can be caused by demyelinating lesions. Parkinsonism, dystonia, and other types of myoclonus, however, often appear to be coincidental.
除震颤外，与多发性硬化症（MS）相关的运动障碍（MD）并不常见。我们报告了14例新病例，其中9例患有肌张力障碍，3例患有帕金森综合征，2例患有肌阵挛。我们还回顾了文献中的135例此类病例。通过对个体运动障碍及所描述病变部位的分析，我们得出结论，阵发性肌张力障碍（强直性痉挛）、舞蹈症/手足徐动症和腭肌阵挛可由脱髓鞘病变引起。然而，帕金森综合征、肌张力障碍和其他类型的肌阵挛似乎常常是巧合。
