van Berkel T F, Erdman R A, Breeman A, Boersma H, van den Brand M J
Afd. Cardiologie, Academisch Ziekenhuis Rotterdam-Dijkzigt.
Ned Tijdschr Geneeskd. 1995 Aug 26;139(34):1733-7.
To determine the differences in quality of life between patients who had a coronary artery bypass graft (CABG) and patients who had a percutaneous transluminal coronary angioplasty (PTCA).
Comparative and prospective study.
Rotterdam, the Netherlands.
91 patients with multi-vessel coronary disease who had been randomised to CABG (n = 37) or PTCA (n = 54), as participants in the CABRI study (Coronary angioplasty or bypass revascularisation investigation) completed several psychological questionnaires. Besides, the severity of angina pectoris after the procedure was estimated using the Canadian Cardiovascular Society score. In a subpopulation of 36 patients (CABG:14; PTCA:22) the quality of life just before the intervention was measured, also using psychological questionnaires.
A significant difference in angina pectoris was found between the two groups. The PTCA group experienced more chest pain (p < 0.01), at an average of 2.6 years after the intervention. The quality of life aspects did not differ between the two groups, except for 'social inhibition' (p < 0.05): the PTCA group experienced more problems and had less energy (p < 0.01). No significant differences between the PTCA and CABG groups were found regarding to the change in quality of life caused by the intervention.
The persistent angina pectoris and social inhibition among patients who have had a PTCA need further study.
确定接受冠状动脉搭桥术(CABG)的患者与接受经皮腔内冠状动脉成形术(PTCA)的患者在生活质量上的差异。
比较性前瞻性研究。
荷兰鹿特丹。
作为CABRI研究(冠状动脉成形术或搭桥血运重建研究)的参与者,91例多支冠状动脉疾病患者被随机分为CABG组(n = 37)或PTCA组(n = 554),他们完成了几份心理问卷。此外,术后使用加拿大心血管学会评分评估心绞痛的严重程度。在36例患者的亚组中(CABG组:14例;PTCA组:22例),同样使用心理问卷测量干预前的生活质量。
两组之间在心绞痛方面存在显著差异。PTCA组在干预后平均2.6年时经历了更多胸痛(p < 0.01)。除了“社交抑制”方面(p < 0.05),两组在生活质量方面没有差异:PTCA组遇到更多问题且精力更少(p < 0.01)。在干预导致的生活质量变化方面,PTCA组和CABG组之间未发现显著差异。
PTCA术后患者持续存在的心绞痛和社交抑制需要进一步研究。