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[特定蜱传感染病原体对载体唾液保护特性的可能利用]

[The probable utilization of the protective properties of the vector's saliva by the causative agents of specifically tick-borne infections].

作者信息

Alekseev A N, Podboronov V M, Burenkova L A

出版信息

Parazitologiia. 1995 May-Jun;29(3):154-8.

PMID:7567075
Abstract

It is proved that in the tick fluid saliva and in the cement plug produced by Rhipicephalus appendiculatus there are bactericidal substances very similar in their activity to the egg lysozyme. The possible role in the transmission and conservation of the specific tick-borne, insensitive to the lysozyme pathogens such as rickettsiae, tick-borne encephalitides virus and borreliae (pathogen of Lyme disease) is discussed. It is supposed, that bactericidal substances in the cement plug protect accumulated in it the tick-borne pathogens (TBE virus, borreliae) from the compete and destructive influence of the vulgar, mainly coccal microflora and from the purulent inflammation, which hinders not only tick feeding but probably specific tick-borne pathogens spreading in the vertebrate host.

摘要

已证明,在微小牛蜱的体液唾液以及其产生的黏胶塞中,存在杀菌物质,这些杀菌物质的活性与卵溶菌酶非常相似。文中讨论了这些杀菌物质在传播和保存对溶菌酶不敏感的特定蜱传病原体(如立克次氏体、蜱传脑炎病毒和疏螺旋体(莱姆病病原体))方面可能发挥的作用。据推测,黏胶塞中的杀菌物质可保护其中积累的蜱传病原体(蜱传脑炎病毒、疏螺旋体)免受主要为球菌的普通微生物群落的竞争和破坏影响,以及免受化脓性炎症的影响,化脓性炎症不仅会阻碍蜱的进食,还可能阻碍特定蜱传病原体在脊椎动物宿主中的传播。

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