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青少年皮肌炎。病理生理学与疾病表现。

Juvenile dermatomyositis. Pathophysiology and disease expression.

作者信息

Pachman L M

机构信息

Department of Pediatrics, Northwestern University Medical School, Illinois, USA.

出版信息

Pediatr Clin North Am. 1995 Oct;42(5):1071-98. doi: 10.1016/s0031-3955(16)40054-4.

DOI:10.1016/s0031-3955(16)40054-4
PMID:7567187
Abstract

In summary, the child who develops the symptoms of the specific rash, proximal muscle weakness, or fatigue should seek medical care promptly. With the advances in physical and medical therapy, many of the consequences of the disease can now be ameliorated. Data suggest that JDMS and PM may each have a different pathophysiology, but more evidence is needed. The next few years will be exciting as there is a national effort by an increased number of investigators to determine the epidemiologic and genetic factors that influence JDMS disease susceptibility and severity.

摘要

总之,出现特定皮疹、近端肌无力或疲劳症状的儿童应立即就医。随着物理治疗和医学治疗的进步,该疾病的许多后果现在可以得到改善。数据表明,幼年皮肌炎和多发性肌炎可能各有不同的病理生理学,但还需要更多证据。未来几年将会令人兴奋,因为越来越多的研究人员正在全国范围内努力确定影响幼年皮肌炎易感性和严重程度的流行病学和遗传因素。

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