Harcke H T, Grissom L E, Meister M A
Department of Medical Imaging, Alfred I. duPont Institute, Wilmington, DE 19899, USA.
Pediatr Radiol. 1995;25(5):341-3. doi: 10.1007/BF02021697.
Intranasal midazolam offers an attractive alternative for use as a sedative agent for medical imaging studies in children. Its convenient administration and rapid onset are significant advantages over intravenous and oral agents. Because of its short duration, it is effective only for short procedures and as an adjunct to other sedative agents. When younger children present with such requirements, a dose of 0.2 mg/kg has been safe and effective in our experience. We advocate its use with adherence to guidelines for sedation published by the American Academy of Pediatrics.
鼻内给予咪达唑仑为儿童医学影像检查提供了一种有吸引力的镇静剂替代方案。与静脉和口服药物相比，其给药方便且起效迅速是显著优势。由于其作用持续时间短，仅对短时间操作有效，且可作为其他镇静剂的辅助药物。根据我们的经验，年幼儿童有此类需求时，0.2mg/kg的剂量安全有效。我们提倡按照美国儿科学会发布的镇静指南使用该药。
