Fernandez X, Meunier-Salaun M C, Ecolan P, Mormède P
Station de Recherches Porcines, INRA, Saint-Gilles, L'Hermitage, France.
Physiol Behav. 1995 Aug;58(2):337-45. doi: 10.1016/0031-9384(94)00364-b.
Agonistic behavior, neuroendocrine and plasma metabolite changes, and muscle glycogen content were studied in 16 fed and 16 24 h-fasted domestic Large White pigs (100 +/- 5 kg) submitted to dyadic encounters (30 min) in a novel environment. Comparisons were made with corresponding control pigs (eight fed and eight 24 h-fasted animals) kept under resting conditions. At rest, fasting resulted in a significant decrease in plasma insulin, increase in plasma-free fatty acids, and decrease in glycogen content in the predominantly red Semispinalis muscle. Fasted pigs displayed significantly more submissive acts than fed ones. In response to dyadic encounters, fed and fasted pigs showed similar rise in plasma levels of cortisol, catecholamines, and lactate, but stress-induced hyperglycemia was suppressed in food-deprived animals. Fasting enhanced stress-induced glycogen depletion in the predominantly white Longissimus muscle but this effect was significant only in fast-twitch glycolytic fibres (alpha W). In the Semispinalis of fasted pigs, however, dyadic encounters did not induce further glycogen depletion. The present findings suggest that in response to dyadic encounters, fasting-induced changes in glucose metabolism lead to a higher dependence on endogenous energy reserves, i.e., glycogen, in working muscles.
在新环境中，对16头采食后的和16头禁食24小时的家养猪（体重100±5千克的大白猪）进行两两配对相遇（30分钟）实验，研究其攻击行为、神经内分泌和血浆代谢物变化以及肌肉糖原含量。并与处于休息状态的相应对照猪（8头采食后的和8头禁食24小时的动物）进行比较。休息时，禁食导致血浆胰岛素显著降低、血浆游离脂肪酸增加以及主要为红色的半棘肌糖原含量降低。禁食的猪表现出的顺从行为明显多于采食后的猪。在两两配对相遇时，采食后的和禁食的猪血浆皮质醇、儿茶酚胺和乳酸水平出现相似的升高，但食物缺乏的动物应激诱导的高血糖受到抑制。禁食增强了应激诱导的主要为白色的背最长肌糖原消耗，但这种效应仅在快肌糖酵解纤维（αW）中显著。然而，在禁食猪的半棘肌中，两两配对相遇并未诱导进一步的糖原消耗。目前的研究结果表明，在两两配对相遇时，禁食诱导的葡萄糖代谢变化导致工作肌肉对内源性能量储备即糖原的依赖性更高。
