Shieh H S
Microbios. 1978;23(92):87-92.
The effects of arginine analogues on a fish pathogen, Aeromonas salmonicida, were investigated. This organism proved to be resistant in various degrees to most arginine analogues tested but was found to be sensitive to arginine hydroxamate. Inhibition of growth by arginine hydroxamate was reversed by the addition of arginine to the bacterial culture. Incorporation of 14C from 14C-amino acids, namely, guanidoarginine, glutamate, asparate, alanine, isoleucine, serine, methyl-methionine, and cystine was affected.
研究了精氨酸类似物对鱼类病原菌杀鲑气单胞菌的影响。结果表明,该菌对大多数测试的精氨酸类似物具有不同程度的抗性,但对异羟肟酸精氨酸敏感。向细菌培养物中添加精氨酸可逆转异羟肟酸精氨酸对生长的抑制作用。14C-氨基酸(即胍基精氨酸、谷氨酸、天冬氨酸、丙氨酸、异亮氨酸、丝氨酸、甲基甲硫氨酸和胱氨酸)中14C的掺入受到影响。