Balcázar José Luis, Vendrell Daniel, de Blas Ignacio, Ruiz-Zarzuela Imanol, Múzquiz José Luis
Laboratory of Fish Pathology, University of Zaragoza, Zaragoza, Spain.
J Mol Microbiol Biotechnol. 2009;17(3):153-7. doi: 10.1159/000226588. Epub 2009 Jun 26.
Aeromonas salmonicida is the etiological agent of furunculosis in salmonid fish. This pathogen is important from an epizootic perspective because fish surviving an outbreak can remain lifelong asymptomatic carriers, serving as reservoirs of infection. As a result, the early detection and the control of infection are essential to prevent the spread of new furunculosis outbreaks. We have thus analyzed the effect of probiotic administration on the incidence of A. salmonicida in brown trout (Salmo trutta), that were subjected to temperature stress. Treatment with probiotic strains (Lactococcus lactis CLFP 100 and Leuconostoc mesenteroides CLFP 196) resulted in a higher survival rate after challenge, activation of phagocytic cells in the head kidney, and a lower rate of pathogen proliferation in the intestine as determined by real-time PCR.
杀鲑气单胞菌是鲑科鱼类疖疮病的病原体。从 epizootic（此处可能有误，推测为 epizootiological，即流行病学的）角度来看，这种病原体很重要，因为在疫情爆发中存活下来的鱼类可能会终生无症状携带，成为感染源。因此，早期检测和感染控制对于防止新的疖疮病疫情传播至关重要。我们分析了益生菌给药对遭受温度应激的褐鳟（Salmo trutta）中杀鲑气单胞菌发病率的影响。用益生菌菌株（乳酸乳球菌CLFP 100和肠膜明串珠菌CLFP 196）进行治疗后，攻毒后的存活率更高，头肾中的吞噬细胞被激活，并且通过实时PCR测定，肠道中病原体的增殖率更低。
