猪主要组织相容性复合体（SL-A）的血清学定义特异性

Serologically defined specificities of the pig main histocompatibility complex (SL-A).

作者信息

Hruban V, Simon M, Hradecký J, Pazdera J

出版信息

Anim Blood Groups Biochem Genet. 1977;8(2):85-92. doi: 10.1111/j.1365-2052.1977.tb01631.x.

DOI:10.1111/j.1365-2052.1977.tb01631.x

Abstract

Six antigens detectable by the complement-dependent lymphocytotoxic technique were determined in pigs by six groups of alloimmune sera. It was confirmed that these specificities are controlled by the main histocompatibility region (SL-A). Serological and genetic studies showed that the given specificities (provisionally designated L1 to L6) form at least 6 haplotypes. In addition, family studies confirmed the linkaged between SL-A region and C blood group locus. Maximum lod score values are in recombination fraction omicron = 0.2.

摘要

通过六组同种免疫血清在猪中测定了六种可通过补体依赖性淋巴细胞毒性技术检测到的抗原。已证实这些特异性由主要组织相容性区域（SL-A）控制。血清学和遗传学研究表明，给定的特异性（暂定为L1至L6）形成至少6种单倍型。此外，家系研究证实了SL-A区域与C血型位点之间的连锁关系。最大lod分数值在重组分数omicron = 0.2处。