Kam R M, Teo W S, Gunawan S A, Tan S H, Tan A T
Department of Cardiology, Singapore General Hospital.
Singapore Med J. 1995 Feb;36(1):68-73.
To review our experience with the upright tilt table test for the diagnosis of vasovagal syncope in a group of unselected patients with a history of syncope or presyncope.
179 patients with a history of syncope or presyncope were subjected to upright tilt test. After carotid sinus massage to exclude carotid sinus hypersensitivity, the patients were tilted on a motorised tilt table with footplate support to an angle of sixty to seventy degrees for thirty minutes. If syncope was not induced, isoprenaline was then infused for a further fifteen minutes. A positive response was defined as fulfilling at least two out of three criteria: (i) syncope or presyncope similar to the spontaneous episodes of syncope, (ii) relative slowing of the heart rate at the onset of symptoms, (iii) drop of systolic pressure to less than 90 mmHg or by more than 50 mmHg.
Continuous variables are expressed as mean values +/- one standard deviation and analysed for statistical significance by the unpaired Student's t-test. Chi-squared test with continuity correction was used for dichotomous variables.
Ninety-four patients (53%) were positive for vasovagal syncope. Fourteen patients (8%) were positive at baseline tilt. An additional 80 patients (45%) were positive with the use of isoprenaline. Ten percent of the positive responses were purely cardioinhibitory, 10% purely vasodepressor and 80% mixed. The commonest cardiac rhythm during a positive response was junctional rhythm (46%) followed by sinus rhythm (44%). Sinus arrest with ventricular standstill occurred in only 5%. Accelerated idioventricular rhythm, 2:1 atrioventricular block and ventricular bigeminy accounted for the remaining 5%.
The upright tilt table test is useful for the diagnosis of vasovagal syncope.
回顾我们在一组无特定选择标准、有晕厥或晕厥前症状病史的患者中,使用直立倾斜试验诊断血管迷走性晕厥的经验。
179例有晕厥或晕厥前症状病史的患者接受直立倾斜试验。在进行颈动脉窦按摩以排除颈动脉窦过敏后,患者在带有脚板支撑的电动倾斜台上倾斜至60至70度,持续30分钟。如果未诱发晕厥,则随后输注异丙肾上腺素15分钟。阳性反应定义为满足以下三项标准中的至少两项:(i)晕厥或晕厥前症状类似于自发晕厥发作,(ii)症状发作时心率相对减慢,(iii)收缩压降至90 mmHg以下或下降超过50 mmHg。
连续变量以平均值±一个标准差表示,并通过非配对学生t检验分析其统计学意义。对二分变量使用连续性校正的卡方检验。
94例患者(53%)血管迷走性晕厥呈阳性。14例患者(8%)在基线倾斜时呈阳性。另外80例患者(45%)在使用异丙肾上腺素后呈阳性。阳性反应中10%为单纯心脏抑制型,10%为单纯血管减压型,80%为混合型。阳性反应期间最常见的心律是交界性心律(46%),其次是窦性心律(44%)。窦性停搏伴心室停搏仅占5%。加速性室性自主心律、2:1房室传导阻滞和室性二联律占其余5%。
直立倾斜试验对血管迷走性晕厥的诊断有用。