Brembilla-Perrot B, Marçon F, Worms A M, Gasparini J, Grentzinger A, Retournay G, Danchin N
Service de cardiologie A, CHU de Brabois, Vandoeuvre-lès-Nancy.
Arch Mal Coeur Vaiss. 1996 Apr;89(4):431-4.
The diagnosis of vasovagal malaise or syncope, suspected from the clinical history, may be confirmed by the tilt test. The aim of this study was to assess the effects of age on the results of this test in 346 patients who had unexplained malaise or syncope. Thirty-one patients were 7 to 19 years of age (group I), 59 were 20 to 40 (group II), 72 were 41 to 60 (group III) and 184 were 61 to 85 years old (group IV). The patients were maintained in the dorsal decubitus position for 20 minutes and then raised to 70 degrees until a malaise was observed or for a maximum of 40 minutes. The malaise or syncope was reproduced by the tilt test in 135 cases (39%). The number of positive responses was comparable in group I, II, III and IV (45, 42, 32 and 40%, respectively). The time before the malaise occurred was also similar in the four groups (17, 19, 15 and 20 minutes, respectively). Two responses to the tilt test characterised the different age groups: the greater number of malaises occurring independently of a drop in blood pressure or change in heart rate ("psychiatric" syncope) in group II compared with groups I, III and IV (40% versus 7, 9 and 9.5%); the higher frequency of pure vasodepressive forms in group IV compared with groups I, II and III (66% versus 28.5, 32 and 39%). In conclusion, the probability of a positive tilt test does not change with age. The mechanisms of the symptoms produced is the only difference observed with age.
根据临床病史怀疑为血管迷走性不适或晕厥,可通过直立倾斜试验来确诊。本研究旨在评估年龄对346例不明原因不适或晕厥患者该试验结果的影响。31例患者年龄在7至19岁(第一组),59例年龄在20至40岁(第二组),72例年龄在41至60岁(第三组),184例年龄在61至85岁(第四组)。患者先仰卧位保持20分钟,然后抬高至70度,直至出现不适或最长持续40分钟。直立倾斜试验诱发不适或晕厥135例(39%)。第一组、第二组、第三组和第四组的阳性反应数量相当(分别为45%、42%、32%和40%)。四组出现不适前的时间也相似(分别为17分钟、19分钟、15分钟和20分钟)。直立倾斜试验的两种反应在不同年龄组有所不同:与第一组、第三组和第四组相比,第二组中更多的不适独立于血压下降或心率变化而发生(“精神性”晕厥,40%对7%、9%和9.5%);与第一组、第二组和第三组相比,第四组中单纯血管抑制型的发生率更高(66%对28.5%、32%和39%)。总之,直立倾斜试验阳性的概率不会随年龄而改变。观察到的年龄差异仅在于所产生症状的机制。