Terui S, Terauchi T, Abe H, Muramatsu Y, Fukuma H, Beppu Y, Yokoyama R
Division of Nuclear Medicine, National Cancer Center Hospital, Tokyo, Japan.
Skeletal Radiol. 1995 Jul;24(5):331-6. doi: 10.1007/BF00197060.
The purpose of this study was to investigate technetium-99m pertechnetate (Tc-99m) as a tumor-scanning agent in patients with extra-abdominal fibromatosis, and to establish the sensitivity of this type of scintigraphy. Eleven patients with extra-abdominal fibromatosis were studied: all but one having postsurgical recurrences. Of the 11 patients, diagnosed histologically, 5 underwent repeated Tc-99m scintigraphic follow-up examinations. The injected 370 MBq Tc-99m gave us an early scintigram within 10 min and a delayed one 2 h later. For adequate comparison, the region of interest (ROI) of the scintigram was placed over the tumor. The tumor-to-background (T/BG) count ratio was computed. Extra-abdominal fibromatoses, even recurrences, were demonstrated scintigraphically in both the early and the delayed phase, in all 11 patients. The average T/BG ratio was 2.11 in the early scintigram and 2.15 in the delayed one. The sensitivity and the specificity were both 100%. Tc-99m scintigraphy has proved useful in detecting extra-abdominal fibromatoses and in the follow-up of patients.
本研究的目的是探讨高锝[99mTc]酸盐（Tc-99m）作为腹外纤维瘤病患者的肿瘤扫描剂，并确定这种闪烁扫描法的敏感性。对11例腹外纤维瘤病患者进行了研究：除1例患者外，其余均有术后复发。在这11例经组织学诊断的患者中，5例接受了Tc-99m闪烁扫描随访检查。注射370MBq的Tc-99m后，在10分钟内获得早期闪烁图像，2小时后获得延迟图像。为了进行充分比较，将闪烁图像的感兴趣区（ROI）置于肿瘤上。计算肿瘤与背景（T/BG）计数比。在所有11例患者中，腹外纤维瘤病，甚至复发灶，在早期和延迟期闪烁扫描中均显示出来。早期闪烁图像的平均T/BG比为2.11，延迟图像的平均T/BG比为2.15。敏感性和特异性均为100%。Tc-99m闪烁扫描已被证明在检测腹外纤维瘤病和患者随访中有用。
