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塞内加尔塞内加尔河流域三角洲某村庄的泌尿生殖系统血吸虫病初步研究。

Preliminary study of urinary schistosomiasis in a village in the delta of the Senegal river basin, Senegal.

作者信息

Verlé P, Stelma F, Desreumaux P, Dieng A, Diaw O, Kongs A, Niang M, Sow S, Talla I, Sturrock R F

机构信息

University of Leiden, The Netherlands.

出版信息

Trans R Soc Trop Med Hyg. 1994 Jul-Aug;88(4):401-5. doi: 10.1016/0035-9203(94)90400-6.

DOI:10.1016/0035-9203(94)90400-6
PMID:7570817
Abstract

Three years after the first cases of urinary schistosomiasis infection were reported in the village of Mbodiene, Senegal, Schistosoma haematobium eggs were found in 87% of the inhabitants of this village; 30% were heavily infected (> 50 eggs per 10 mL urine). The prevalence of infection was very high in all age groups, but children showed more intense infections. No difference between sexes was found. In the special situation of a very high prevalence, test strips for proteinuria and haematuria are not very useful for the individual diagnosis of S. haematobium infection. Six and 12 weeks after treatment with a single dose of praziquantel (40 mg/kg), S. haematobium eggs were found in 25% and 30% of the treated subjects, respectively. Bulinus globosus was identified as intermediate host, but other snail vectors may also play a role. S. mansoni eggs were found in 1% of the population. Both S. haematobium and S. mansoni are spreading in the delta of the Senegal river.

摘要

在塞内加尔姆博迪埃村报告首例泌尿血吸虫病感染病例三年后,在该村庄87%的居民中发现了埃及血吸虫卵;30%的居民感染严重(每10毫升尿液中虫卵>50个)。所有年龄组的感染率都很高,但儿童的感染更为严重。未发现性别差异。在感染率非常高的特殊情况下,蛋白尿和血尿检测试纸对埃及血吸虫感染的个体诊断不太有用。在单剂量吡喹酮(40毫克/千克)治疗6周和12周后,分别在25%和30%的治疗对象中发现了埃及血吸虫卵。球形水泡螺被确定为中间宿主,但其他螺类媒介可能也起作用。在1%的人群中发现了曼氏血吸虫卵。埃及血吸虫和曼氏血吸虫都在塞内加尔河三角洲传播。

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