McEntee K, Grauwels M, Clercx C, Henroteaux M
Small Animal Clinic, Department of Internal Medicine, Faculty of Veterinary Medicine, University of Liege, Belgium.
Vet Hum Toxicol. 1995 Jun;37(3):234-6.
A case of overdosage with closantel, a salicynalide derivative, in a dog is described. The dog received 6 times the recommended dosage. Closantel induced optic neuritis, retinal degeneration, partial deafness, hepatotoxicosis and myopathy. Only the blindness was irreversible. The therapy included albumin administration to reduce the acute toxicity of closantel.
本文描述了一例犬过量服用沙立辛酰胺衍生物氯氰碘柳胺的病例。该犬服用剂量为推荐剂量的6倍。氯氰碘柳胺导致视神经炎、视网膜变性、部分失聪、肝中毒和肌病。仅失明不可逆。治疗措施包括给予白蛋白以降低氯氰碘柳胺的急性毒性。
