Jusa E R, Inaba Y, Ishibashi K, Noda M
Department of Veterinary Epizootiology, College of Agriculture and Veterinary Medicine, Nihon University, Kanagawa, Japan.
Vet Microbiol. 1995 Jul;45(2-3):251-8. doi: 10.1016/0378-1135(95)00040-h.
Heparin inhibited the hemagglutinin activity of Akabane and Aino viruses. The minimal inhibitory concentration of heparin required to inhibit 8 hemagglutination (HA) U of Akabane and Aino viruses was 10 U/ml. Goose erythrocytes failed to combine with the HA inhibitory factor of heparin. On the other hand, goose erythrocytes treated with heparinase had greatly reduced agglutinability by Akabane virus. Virus-heparin complex formation was observed by sedimenting heparin with the virus particles.
肝素抑制赤羽病病毒和艾诺病毒的血凝素活性。抑制赤羽病病毒和艾诺病毒8个血凝（HA）单位所需的肝素最小抑制浓度为10 U/ml。鹅红细胞未能与肝素的HA抑制因子结合。另一方面，用肝素酶处理的鹅红细胞被赤羽病病毒凝集的能力大大降低。通过将肝素与病毒颗粒一起沉淀观察到病毒-肝素复合物的形成。
