Stelmasiak Z, Solski J, Jakubowska B
Department of Clinical Analytics, School of Medicine, Lublin, Poland.
Acta Neurol Scand. 1995 Jul;92(1):109-11. doi: 10.1111/j.1600-0404.1995.tb00476.x.
There are few reports of Mg in MS and none dealing with Mg content in erythrocytes. Mg concentration was determined in serum and in erythrocytes with the help of a BIOTROL Magnesium Calmagite colorimetric method (average sensitivity: 0.194 A per mmol/I) and a Hitachi autoanalyzer in 24 MS patients (7 men and 17 women, age 29-60; 37 years on average with the duration of the disease: 3-19; 11 years on average, at clinical disability stages according to the Kurtzke scale: 1-7; 3.2 on average, in remission stage. A statistically significant decrease (p < 0.001) of Mg concentration in erythrocytes and no changes in plasma of MS patients were found. The results obtained suggest the presence of changes in membrane of erythrocytes which could be connected with their shorter life and with affection of their function.
关于镁在多发性硬化症（MS）中的报道很少，且没有涉及红细胞中镁含量的研究。采用BIOTROL镁钙镁试剂比色法（平均灵敏度：每毫摩尔/升0.194吸光度）和日立自动分析仪，对24例MS患者（7名男性和17名女性，年龄29 - 60岁；平均37岁，病程3 - 19年；平均11年，根据Kurtzke量表处于临床残疾阶段：1 - 7级；平均3.2级，处于缓解期）的血清和红细胞中的镁浓度进行了测定。结果发现，MS患者红细胞中的镁浓度有统计学意义的显著降低（p < 0.001），而血浆中的镁浓度没有变化。所得结果表明，红细胞膜存在变化，这可能与其较短的寿命及其功能受到影响有关。
