Menniti-Ippolito F, Spila-Alegiani S, Vanacore N, Bonifati V, Diana G, Meco G, Raschetti R
Department of Epidemiology, La Sapienza University, Rome, Italy.
Acta Neurol Scand. 1995 Jul;92(1):49-54. doi: 10.1111/j.1600-0404.1995.tb00465.x.
The objective of the study was to estimate the prevalence of parkinsonism in the Province of Rome using antiparkinsonian prescription histories from 1986 to 1991.
A subject was defined as a case of parkinsonism if he/she had received "specific" and "consistent" antiparkinsonian therapy in the study period.
In November 1990, 6,572 patients were defined as prevalent cases of parkinsonism. The crude prevalence ratio, for the total population of the Province of Rome, is 173.5 per 100,000 inhabitants (165.9 per 100,000 in men and 180.5 per 100,000 in women). The method was validated by record-linkage with clinical records of all patients visited during 1990 at the Department of Neurological Sciences of the University of Rome "La Sapienza". The sensitivity of the prevalence study was 83.6%.
The use of a computerized data base of all prescription data, routinely collected for administrative purposes, enabled us to obtain a prevalence estimate based on a very large population, with low costs and in a relatively short time.
本研究的目的是利用1986年至1991年的抗帕金森病处方记录来估计罗马省帕金森综合征的患病率。
如果一个人在研究期间接受了“特定”且“持续”的抗帕金森病治疗，则将其定义为帕金森综合征病例。
1990年11月，6572名患者被定义为帕金森综合征的现患病例。罗马省总人口的粗患病率为每10万居民173.5例（男性为每10万居民165.9例，女性为每10万居民180.5例）。该方法通过与1990年罗马“La Sapienza”大学神经科学系诊治的所有患者的临床记录进行记录链接进行了验证。患病率研究的敏感性为83.6%。
使用为行政目的常规收集的所有处方数据的计算机化数据库，使我们能够以低成本且在相对较短的时间内，基于非常大的人群获得患病率估计值。
