de Carvalho M, Conceição I, Alves M, Luís M L
Department of Neurology, Santa Maria University Hospital, Lisbon, Portugal.
Acta Neurol Scand. 1995 Jul;92(1):72-6. doi: 10.1111/j.1600-0404.1995.tb00470.x.
Spinal cord compression (SCC) often presents a similar clinical picture to amyotrophic lateral sclerosis (ALS). An early differential diagnosis is important because SCC is a potentially treatable clinical disorder. We carried out a longitudinal study of 43 patients with an initial diagnosis of ALS, in order to ascertain the percentage of patients with SCC, and to evaluate the usefulness of somatosensory evoked potentials (SEPs) in early diagnosis. Thirty-three patients had a final diagnosis of ALS and 8 of SCC. SEPs central conduction was abnormal in 3 ALS and 7 SCC patients, respectively (Fisher exact test, p < 0.05). We concluded that SEPs investigation is useful in the differential diagnosis between ALS and SCC patients with pure motor signs.
脊髓压迫症（SCC）通常呈现出与肌萎缩侧索硬化症（ALS）相似的临床表现。早期鉴别诊断很重要，因为SCC是一种潜在可治疗的临床疾病。我们对43例初步诊断为ALS的患者进行了一项纵向研究，以确定SCC患者的比例，并评估体感诱发电位（SEP）在早期诊断中的有用性。33例患者最终诊断为ALS，8例为SCC。分别有3例ALS患者和7例SCC患者的SEP中枢传导异常（Fisher精确检验，p < 0.05）。我们得出结论，SEP检查对于鉴别具有纯运动体征的ALS和SCC患者很有用。
