Zenner H P, Zimmermann U
Department of Otolaryngology, University of Tübingen, Germany.
Acta Otolaryngol. 1995 Jul;115(4):484-7. doi: 10.3109/00016489509139352.
Evokation of caloric nystagmus in microgravity argues against thermal convection as a sufficient explanation for a caloric nystagmic response. By contrast, caloric nystagmus observed in weightlessness suggests a gravity independent mechanism. Here we demonstrate that direct caloric stimulation of isolated living vestibular hair cells from the guinea pig evoked mechanical responses of the sensory cells. Heating of the mechanoreceptor cells from 37 degrees C to 42 degrees C resulted in elongation cooling of the cells from 37 degrees C to 30 degrees C induced shortening of vestibular hair cells. The observed mechanism might contribute to the caloric evokation of a nystagmus both on earth and in orbit.
在微重力环境下诱发的冷热性眼震表明，热对流不足以解释冷热性眼震反应。相比之下，在失重状态下观察到的冷热性眼震提示存在一种不依赖重力的机制。在此，我们证明对豚鼠分离的活体前庭毛细胞进行直接热刺激可诱发感觉细胞的机械反应。将机械感受器细胞从37摄氏度加热至42摄氏度会导致细胞伸长，而将细胞从37摄氏度冷却至30摄氏度则会引起前庭毛细胞缩短。所观察到的机制可能有助于在地球上和轨道上诱发眼震的冷热刺激。
