Lam B L, Lam S, Walls R C
Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, USA.
Am J Ophthalmol. 1995 Oct;120(4):518-22. doi: 10.1016/s0002-9394(14)72667-4.
Because palpebral fissure asymmetry in horizontal gaze is reportedly common in otherwise normal persons, we determined the prevalence of physiologic palpebral fissure asymmetry for primary and horizontal gazes.
We measured the palpebral fissure height of both eyes of 88 healthy white subjects. Measurements were obtained with high-resolution videography, with the eyes in primary position, in 45-degree right gaze, and in 45-degree left gaze.
Of the 88 subjects, 36 (41%) were male and 52 (59%) were female. The ages ranged from 12 to 50 years, with a mean of 32.5 +/- 9.0 years. When a criterion of equal to or greater than 1 mm was used, the prevalence of physiologic palpebral fissure asymmetry was 5.7% (five of 88) in primary gaze, 18.2% (16 of 88) in right gaze, and 14.8% (13 of 88) in left gaze. The largest observed palpebral fissure asymmetry was 2.1 mm. After correcting for any existing fissure asymmetry in primary gaze, two-tailed trivariate analysis of variance showed that the fissure of the adducting eye tended to be wider. The mean increase in the palpebral fissure of the adducting eye was 0.12 mm for right gaze (P = .052) and 0.13 mm for left gaze (P = .034). Additionally, a chi 2 test indicated that the occurrence of wider adducting eye in both right and left gazes was highly significant (P = .0023).
In this sample of white subjects, palpebral fissure height asymmetry increased in horizontal gaze to the right and to the left, which is in part because of a tendency of the adducting eye to widen slightly. In contrast to previous reports, the prevalence of palpebral fissure asymmetry was low, and the abducting eye did not widen significantly.
据报道，水平注视时睑裂不对称在其他方面正常的人群中很常见，我们确定了第一眼位和水平注视时生理性睑裂不对称的患病率。
我们测量了88名健康白人受试者双眼的睑裂高度。使用高分辨率摄像技术在第一眼位、向右45度注视和向左45度注视时进行测量。
88名受试者中，36名（41%）为男性，52名（59%）为女性。年龄范围为12至50岁，平均年龄为32.5±9.0岁。当使用等于或大于1毫米的标准时，第一眼位生理性睑裂不对称的患病率为5.7%（88名中的5名），向右注视时为18.2%（88名中的16名），向左注视时为14.8%（88名中的13名）。观察到的最大睑裂不对称性为2.1毫米。在纠正第一眼位中任何现有的睑裂不对称后，双尾三变量方差分析显示内收眼的睑裂变宽。向右注视时内收眼睑裂平均增加0.12毫米（P = 0.052），向左注视时为0.13毫米（P = 0.034）。此外，卡方检验表明，左右注视时内收眼变宽的发生率非常显著（P = 0.0023）。
在这个白人受试者样本中，水平向右和向左注视时睑裂高度不对称增加，部分原因是内收眼有轻微变宽的趋势。与之前的报道相反，睑裂不对称的患病率较低，外展眼没有明显变宽。
