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上睑裂高度在原发性注视位置对泪膜稳定性的影响。

THE EFFECT OF PALPEBRAL FISSURE HEIGHT IN PRIMARY GAZE POSITION ON TEAR FILM STABILITY.

机构信息

Servus Anda Polyclinic for Ophthalmology, Split, Croatia.

Department of Ophthalmology, Zagreb University Hospital Center, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2023 Aug;62(2):283-290. doi: 10.20471/acc.2023.62.02.05.

Abstract

This study aimed to investigate the effect of palpebral fissure height in primary gaze position in healthy individuals on tear film stability. In this cross-sectional study, 120 subjects (60 male and female each) were enrolled and divided according to age into two groups, i.e., group 1 (aged 18-50 years) and group 2 (aged 51 and older). Palpebral fissure height on both eyes was measured in primary gaze position with a clear plastic ruler held in a central vertical position between the upper and lower lid margin, and the standard tear break-up time (TBUT) test was performed to evaluate tear film stability. Palpebral fissure height was significantly higher in younger than older subjects in all measurements on both eyes (p<0.001), and TBUT was shorter in older than in younger subjects. In all subjects included in the study, palpebral fissure height was not related to TBUT (p=0.589). However, analyzing the two age groups separately, a significant negative correlation was found between the palpebral fissure height and TBUT in both groups of younger (p<0.001) and older (p=0.009) subjects. In conclusion, an enlarged exposed ocular surface due to higher palpebral fissure height in healthy individual's primary gaze position negatively affects tear film stability expressed by TBUT.

摘要

本研究旨在探讨正常人第一眼位时睑裂高度对泪膜稳定性的影响。在这项横断面研究中,共纳入 120 名受试者(男女各 60 名),并根据年龄分为两组,即第 1 组(18-50 岁)和第 2 组(51 岁及以上)。在第一眼位,使用透明塑料直尺置于上、下睑缘中央垂直位置测量双眼睑裂高度,行标准泪膜破裂时间(TBUT)检查以评估泪膜稳定性。所有测量值中,年轻组的睑裂高度均明显高于老年组(p<0.001),且老年组的 TBUT 短于年轻组(p<0.001)。在所有纳入研究的受试者中,睑裂高度与 TBUT 无相关性(p=0.589)。然而,分别分析两个年龄组,发现年轻组(p<0.001)和老年组(p=0.009)的睑裂高度与 TBUT 呈显著负相关。总之,在健康个体第一眼位时,由于睑裂高度增加导致暴露的眼表增大,会对 TBUT 所表示的泪膜稳定性产生负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e0a/10969636/d5eb43b8fa59/acc-62-283-f1.jpg

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