Marzuk P M, Tardiff K, Leon A C, Hirsch C S, Stajic M, Hartwell N, Portera L
Department of Psychiatry, Cornell University Medical College, New York, NY 10021, USA.
Am J Psychiatry. 1995 Oct;152(10):1520-2. doi: 10.1176/ajp.152.10.1520.
The authors examined the rate of prescription psychotropic drug use among suicide victims at the time of their death.
From a total of 1,970 suicides that occurred in New York City from 1990 to 1992, 1,635 cases that had a complete toxicologic analysis and an injury-death interval of 48 hours or less were assessed at autopsy for the presence of commonly prescribed antidepressants and neuroleptics.
Prescription psychotropic medications were detected in only 16.4% (N = 268) of the suicide victims studied. Demographic factors associated with use of these drugs included female gender and white race. Poisoning accounted for 17.9% (N = 293) of all suicides studied, but antidepressants or neuroleptics were detected in less than half of these victims. Among all suicide victims in whom an antidepressant or neuroleptic was detected, almost half had used lethal methods other than poisoning.
In this study, most individuals who committed suicide in New York City were not taking prescription psychotropic medications at the time of their death and either were not receiving pharmacotherapy or were noncompliant.
作者研究了自杀受害者死亡时使用处方精神药物的比例。
在1990年至1992年纽约市发生的1970起自杀事件中，对1635例进行了完整毒理学分析且损伤至死亡间隔为48小时或更短的病例进行尸检，以确定是否存在常用的抗抑郁药和抗精神病药。
在所研究的自杀受害者中，仅16.4%（N = 268）检测出使用了处方精神药物。与使用这些药物相关的人口统计学因素包括女性和白人。中毒占所有研究自杀事件的17.9%（N = 293），但这些受害者中不到一半检测出使用了抗抑郁药或抗精神病药。在所有检测出使用抗抑郁药或抗精神病药的自杀受害者中，几乎一半使用了除中毒以外的致命方法。
在本研究中，纽约市大多数自杀者死亡时未服用处方精神药物，要么未接受药物治疗，要么未遵医嘱。
