人群中因饮用富含过量维生素D的牛奶而产生的亚临床健康影响。
Subclinical health effects in a population exposed to excess vitamin D in milk.
作者信息
Scanlon K S, Blank S, Sinks T, Lett S, Mueller P, Freedman D S, Serdula M, Falk H
机构信息
Division of Nutrition, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341-3724, USA.
出版信息
Am J Public Health. 1995 Oct;85(10):1418-22. doi: 10.2105/ajph.85.10.1418.
To evaluate subclinical health effects of excess vitamin D, a cross-sectional study was conducted of persons consuming milk from a dairy that had overfortified milk for at least 4 years. Milk consumption, sunlight exposure, medical symptoms, serum 25-hydroxyvitamin D (25[OH]D), serum and urinary calcium, and indicators of renal function were measured. Increased milk consumption was associated with increased serum 25(OH)D and urinary calcium. However, the prevalences of elevated serum 25(OH)D and calcium were no greater than expected, and data indicated normal renal function. It was concluded that most persons exposed to excess vitamin D exhibited no measurable adverse subclinical effects.
为评估过量维生素D的亚临床健康影响，对饮用一家至少4年过度强化牛奶的乳制品厂所产牛奶的人群进行了一项横断面研究。测量了牛奶摄入量、阳光照射、医学症状、血清25-羟基维生素D（25[OH]D）、血清和尿钙以及肾功能指标。牛奶摄入量增加与血清25(OH)D和尿钙增加有关。然而，血清25(OH)D和钙升高的患病率并不高于预期，且数据表明肾功能正常。得出的结论是，大多数暴露于过量维生素D的人没有表现出可测量的亚临床不良影响。
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