Nielsen G P, O'Connell J X, Dickersin G R, Rosenberg A E
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Am J Surg Pathol. 1995 Nov;19(11):1272-6. doi: 10.1097/00000478-199511000-00007.
Chondroid lipoma is a recently described variant of lipoma with unusual morphologic features. Although classified as a fatty neoplasm, its phenotype is uncertain because it has not been determined whether cartilage is a real component or only simulated by light microscopy and whether the adipocytes demonstrate white or brown fat differentiation, issues that can be resolved only by electron microscopy. We present two cases of chondroid lipoma that ultrastructurally showed abundant intracytoplasmic lipid and glycogen and numerous pinocytotic vesicles, characteristic of white adipocytes. These findings support the conclusion that these tumors are composed solely of fat without true cartilage differentiation.
软骨样脂肪瘤是一种最近描述的具有不寻常形态特征的脂肪瘤变体。尽管被归类为脂肪性肿瘤，但其表型尚不确定，因为尚未确定软骨是真正的组成成分还是仅在光学显微镜下被模拟，以及脂肪细胞是表现为白色还是棕色脂肪分化，这些问题只有通过电子显微镜才能解决。我们报告两例软骨样脂肪瘤，超微结构显示丰富的胞质内脂质和糖原以及大量吞饮小泡，这是白色脂肪细胞的特征。这些发现支持这些肿瘤仅由脂肪组成而无真正软骨分化的结论。
