Bonavina L, Segalin A, Fumagalli U, Peracchia A
Department of General and Oncologic Surgery, University of Milan, Italy.
Ann Chir Gynaecol. 1995;84(2):175-8.
From January 1976 to December 1994, out of 605 patients with reflux oesophagitis, 166 (27.4%) presented with an oesophageal stricture, and 68 of these (40.9%) underwent surgical therapy. Thirteen of the 68 patients (19.1%) had an associated Barrett's oesophagus. Oesophageal manometry revealed scleroderma in nine individuals (13.2%). The stricture was undilatable in 11 patients (16.1%) observed before 1985. An oesophageal-sparing operation was performed in the majority of patients: fundoplication (n = 39), Collis gastroplasty plus fundoplication (n = 10), and total duodenal diversion (n = 4). Oesophageal resection was performed in 15 patients (22%); 12 of these individuals were operated on before 1985. The mortality rate was 4.4%: two patients died of necrosis of the interposed colon and one of acute pancreatitis. The average follow-up time was 27 months (8-136). Oesophageal-sparing procedures significantly reduced the need for further endoscopic dilatation (P < 0.001). Standard fundoplication was successful in 30 out of 39 patients (77%). Reasons for a failed fundoplication were a long, hard stricture, an ineffective partial wrap in patients with unrecognized short oesophagus, or underlying scleroderma. Regression of Barrett's mucosa was not recorded with any of the conservative surgical procedures.
1976年1月至1994年12月,在605例反流性食管炎患者中,166例(27.4%)出现食管狭窄,其中68例(40.9%)接受了手术治疗。68例患者中有13例(19.1%)合并巴雷特食管。食管测压显示9例(13.2%)患有硬皮病。1985年前观察的11例患者(16.1%)的狭窄无法扩张。大多数患者接受了保留食管的手术:胃底折叠术(n = 39)、科利斯胃成形术加胃底折叠术(n = 10)和全十二指肠转位术(n = 4)。15例患者(22%)接受了食管切除术;其中12例在1985年前接受手术。死亡率为4.4%:2例患者死于间置结肠坏死,1例死于急性胰腺炎。平均随访时间为27个月(8 - 136个月)。保留食管的手术显著减少了进一步内镜扩张的需求(P < 0.001)。标准胃底折叠术在39例患者中的30例(77%)成功。胃底折叠术失败的原因是狭窄长且硬、对未识别的短食管患者进行的部分包裹无效或存在潜在的硬皮病。任何一种保守手术均未记录到巴雷特黏膜的消退。