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反流性食管炎所致良性狭窄的外科治疗

Surgical management of benign stricture from reflux oesophagitis.

作者信息

Bonavina L, Segalin A, Fumagalli U, Peracchia A

机构信息

Department of General and Oncologic Surgery, University of Milan, Italy.

出版信息

Ann Chir Gynaecol. 1995;84(2):175-8.

PMID:7574377
Abstract

From January 1976 to December 1994, out of 605 patients with reflux oesophagitis, 166 (27.4%) presented with an oesophageal stricture, and 68 of these (40.9%) underwent surgical therapy. Thirteen of the 68 patients (19.1%) had an associated Barrett's oesophagus. Oesophageal manometry revealed scleroderma in nine individuals (13.2%). The stricture was undilatable in 11 patients (16.1%) observed before 1985. An oesophageal-sparing operation was performed in the majority of patients: fundoplication (n = 39), Collis gastroplasty plus fundoplication (n = 10), and total duodenal diversion (n = 4). Oesophageal resection was performed in 15 patients (22%); 12 of these individuals were operated on before 1985. The mortality rate was 4.4%: two patients died of necrosis of the interposed colon and one of acute pancreatitis. The average follow-up time was 27 months (8-136). Oesophageal-sparing procedures significantly reduced the need for further endoscopic dilatation (P < 0.001). Standard fundoplication was successful in 30 out of 39 patients (77%). Reasons for a failed fundoplication were a long, hard stricture, an ineffective partial wrap in patients with unrecognized short oesophagus, or underlying scleroderma. Regression of Barrett's mucosa was not recorded with any of the conservative surgical procedures.

摘要

1976年1月至1994年12月,在605例反流性食管炎患者中,166例(27.4%)出现食管狭窄,其中68例(40.9%)接受了手术治疗。68例患者中有13例(19.1%)合并巴雷特食管。食管测压显示9例(13.2%)患有硬皮病。1985年前观察的11例患者(16.1%)的狭窄无法扩张。大多数患者接受了保留食管的手术:胃底折叠术(n = 39)、科利斯胃成形术加胃底折叠术(n = 10)和全十二指肠转位术(n = 4)。15例患者(22%)接受了食管切除术;其中12例在1985年前接受手术。死亡率为4.4%:2例患者死于间置结肠坏死,1例死于急性胰腺炎。平均随访时间为27个月(8 - 136个月)。保留食管的手术显著减少了进一步内镜扩张的需求(P < 0.001)。标准胃底折叠术在39例患者中的30例(77%)成功。胃底折叠术失败的原因是狭窄长且硬、对未识别的短食管患者进行的部分包裹无效或存在潜在的硬皮病。任何一种保守手术均未记录到巴雷特黏膜的消退。

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