Bonavina L, Segalin A, Pavanello M, Faranda C, Cioffi U, Peracchia A
Istituto di Chirurgia Generale e Oncologia Chirurgica, Università degli Studi di Milano.
Ann Ital Chir. 1995 Sep-Oct;66(5):621-4.
From 1976 to 1993, among 582 patients with reflux esophagitis seen at our Institution, 164 (28%) presented with an esophageal stricture, and 68 of these (41%) underwent surgical treatment. The male to female ratio was 1.6:1, and the median age 51 (range 15-78). Thirteen of the 68 patients (19%) had an associated Barrett's esophagus. Esophageal manometry revealed scleroderma in nine individuals (13%). In 11 patients (16%) observed before 1985 the stricture was not dilatable. Surgical therapy consisted of fundoplication (n = 39), Collis gastroplasty plus fundoplication (n = 10), total duodenal diversion (n = 4), and esophageal resection (n = 15). The mortality rate was 4.4%: two patients died of necrosis of the colon transplant and one of acute pancreatitis. The median follow-up was 27 months (6-129). Esophageal sparing procedures significantly reduced the need of further endoscopic dilatation (p < 0.001). Standard fundoplication was successful in 30 of 39 patients (77%). Regression of Barrett's epithelium was not recorded after any of the conservative surgical procedures.
1976年至1993年期间,在我院就诊的582例反流性食管炎患者中,164例(28%)出现食管狭窄,其中68例(41%)接受了手术治疗。男女比例为1.6:1,中位年龄51岁(范围15 - 78岁)。68例患者中有13例(19%)合并巴雷特食管。食管测压显示9例(13%)患有硬皮病。在1985年前观察的11例患者(16%)中,狭窄无法扩张。手术治疗包括胃底折叠术(n = 39)、科利斯胃成形术加胃底折叠术(n = 10)、全十二指肠转流术(n = 4)和食管切除术(n = 15)。死亡率为4.4%:2例患者死于结肠移植坏死,1例死于急性胰腺炎。中位随访时间为27个月(6 - 129个月)。保留食管的手术显著减少了进一步内镜扩张的需求(p < 0.001)。标准胃底折叠术在39例患者中的30例(77%)取得成功。在任何保守性手术治疗后均未记录到巴雷特上皮的消退。