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[1例术前动脉内灌注化疗后组织学完全缓解的病例]

[A case of histological complete remission by preoperative intraarterial infusion chemotherapy].

作者信息

Taniguchi Y, Matsuo M, Umeki H, Tada M, Kohyama A, Kuwae C, Kitada H, Ohtsuka H

机构信息

Dept. of Gynecology, Tokyo Metropolitan Fuchu Hospital.

出版信息

Gan To Kagaku Ryoho. 1995 Sep;22(11):1702-5.

PMID:7574797
Abstract

We experienced a case of histological complete remission by preoperative intraarterial infusion chemotherapy in the treatment of histologically diagnosed endometrial cancer of well differentiated type. MRI demonstrated invasion of the myometrium to a depth of more than 1/2 and left partial parametrium. This patient was given intra-uterine arterial infusion chemotherapy twice (CDDP & ADM ia, CPA iv). Radical hysterectomy was done 3 weeks after intraarterial infusion chemotherapy. The extirpated uterus was histologically complete remission. Thus, in this case shows that intraarterial infusion chemotherapy is effective for neo-adjuvant chemotherapy of endometrial cancer.

摘要

我们遇到了一例通过术前动脉内灌注化疗实现组织学完全缓解的病例,该病例为组织学诊断的高分化型子宫内膜癌。MRI显示肌层浸润深度超过1/2且累及左侧部分宫旁组织。该患者接受了两次子宫动脉内灌注化疗(顺铂与阿霉素动脉内给药,环磷酰胺静脉内给药)。在动脉内灌注化疗3周后进行了根治性子宫切除术。切除的子宫组织学检查显示完全缓解。因此,该病例表明动脉内灌注化疗对子宫内膜癌的新辅助化疗有效。

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