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[病例报告:子宫内膜癌对腹腔内和动脉内化疗的反应]

[A case report: endometrial carcinoma response to intraperitoneal and intraarterial chemotherapy].

作者信息

Itagaki T, Furusawa Y, Sasaki Y, Kurihara H, Mitsukawa G

机构信息

Dept. of Obstetrics and Gynecology, Mito Red Cross Hospital.

出版信息

Gan To Kagaku Ryoho. 1998 Jul;25(9):1326-9.

PMID:9703819
Abstract

Intraperitoneal and arterial neo-adjuvant chemotherapy were given to one patient with endometrial carcinoma (clear cell adenocarcinoma). She was diagnosed as an inoperable advanced carcinoma (stage IV B) associated with direct invasion of the urinary bladder and pleural effusion. Intraperitoneal infusion therapy with CDDP 100 mg was given every 3 weeks. The patient was also given intra-uterine arterial infusion chemotherapy three times with CDDP and ADM. MRI, CT, and Cystoscopic examinations failed to detect any carcinoma. An optimal operation was performed. In a histological study, the uterine carcinoma was in complete remission. But a degenerative adenocarcinoma was shown at peritoneal dissemination.

摘要

一名子宫内膜癌(透明细胞腺癌)患者接受了腹腔和动脉新辅助化疗。她被诊断为无法手术的晚期癌(IV B期),伴有膀胱直接侵犯和胸腔积液。每3周给予100mg顺铂腹腔灌注治疗。该患者还接受了3次顺铂和阿霉素子宫动脉灌注化疗。MRI、CT和膀胱镜检查均未发现任何癌灶。进行了择期手术。组织学研究显示子宫癌完全缓解。但腹膜播散处显示有退行性腺癌。

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