• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies.

作者信息

Weimann E, Reisbach G, Reinsberg J, Lentze M J

机构信息

Children's Hospital, University of Frankfurt/Main, Germany.

出版信息

Arch Gynecol Obstet. 1995;256(3):125-30. doi: 10.1007/BF01314640.

DOI:10.1007/BF01314640
PMID:7574904
Abstract

Activity levels of cytokines were measured by stimulation of the cell lines NFS-60, 7TD1, and TF-1. In 39 samples of amniotic fluid, levels of Granulocyte-Stimulating Factor (G-CSF) were 1434 +/- 2063 (mean +/- SD) and of Interleukin (IL-6) 546 +/- 1071 pg/ml; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was not detectable. IL-6 was correlated to G-CSF (r = 0.3; p = 0.003). G-CSF (p = 0.0002) and IL-6 (p = 0.006) were influenced by Alpha-Fetoprotein (AFP) and G-CSF by rhesus-incompatibility (p = 0.0004). These findings suggest that cytokines such as IL-6 and G-CSF play some role in physiological and pathological pregnancy.

摘要

相似文献

1
IL-6 and G-CSF levels in amniotic fluid during the second trimester in normal and abnormal pregnancies.
Arch Gynecol Obstet. 1995;256(3):125-30. doi: 10.1007/BF01314640.
2
Granulocyte colony-stimulating factor in preterm and term pregnancy, parturition, and intra-amniotic infection.粒细胞集落刺激因子在早产和足月妊娠、分娩及羊膜腔内感染中的作用
Obstet Gynecol. 2001 Feb;97(2):229-34. doi: 10.1016/s0029-7844(00)01120-0.
3
Expression pattern of cytokines in the different compartments of the feto-maternal unit under various conditions.不同条件下胎儿-母体单位不同隔室中细胞因子的表达模式。
Reprod Fertil Dev. 1995;7(6):1573-80. doi: 10.1071/rd9951573.
4
Cytokine production and visualized effects in the feto-maternal unit. Quantitative and topographic data on cytokines during intrauterine disease.细胞因子在母胎单位中的产生及可视化效应。宫内疾病期间细胞因子的定量和拓扑学数据。
Lab Invest. 1995 Sep;73(3):384-92.
5
Cytokines in fetal blood and amniotic fluid in Rh-immunized pregnancies.Rh免疫妊娠中胎儿血液和羊水中的细胞因子。
Obstet Gynecol. 1995 Aug;86(2):209-13. doi: 10.1016/0029-7844(95)00132-b.
6
Alpha-fetoprotein and hematopoietic growth factors in amniotic fluid.羊水中的甲胎蛋白和造血生长因子。
Obstet Gynecol. 2000 Oct;96(4):588-92. doi: 10.1016/s0029-7844(00)00975-3.
7
Mid-trimester amniotic fluid concentrations of the proinflammatory cytokines IL-6, IL-8, TNF-α, and lipopolysaccharide binding protein in normal pregnancies: a prospective evaluation according to parity, gestational age, and fetal gender.足月妊娠孕妇羊水中促炎细胞因子白细胞介素-6、白细胞介素-8、肿瘤坏死因子-α和脂多糖结合蛋白浓度：根据产次、孕龄和胎儿性别进行的前瞻性评估。
J Perinat Med. 2011 Jul;39(4):403-9. doi: 10.1515/jpm.2011.041. Epub 2011 Jun 24.
8
Inflammatory cytokines and antioxidants in midtrimester amniotic fluid: correlation with pregnancy outcome.中期羊水中的炎症细胞因子和抗氧化剂：与妊娠结局的相关性。
Am J Obstet Gynecol. 2011 Feb;204(2):155.e1-7. doi: 10.1016/j.ajog.2010.08.064. Epub 2010 Oct 14.
9
Granulocyte and granulocyte-macrophage colony-stimulating factors, their receptors and interleukin-3 levels in newborns.新生儿中性粒细胞和粒细胞巨噬细胞集落刺激因子、其受体及白细胞介素-3水平
Turk J Pediatr. 1997 Jul-Sep;39(3):295-301.
10
Interleukin-6, interferon-gamma, interleukin-8, and granulocyte-macrophage colony stimulating factor levels in human amniotic fluid at term.
J Reprod Immunol. 1996 Nov;32(1):89-98. doi: 10.1016/s0165-0378(96)00990-4.

引用本文的文献

1
Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the beta-chain of the interleukin-2 receptor.人羊水缺乏白细胞介素-2和白细胞介素-15，但可与白细胞介素-2受体的β链相互作用。
Immunology. 2000 Mar;99(3):411-7. doi: 10.1046/j.1365-2567.2000.00978.x.

本文引用的文献

1
Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?母胎关系中的双向细胞因子相互作用：成功妊娠是一种Th2现象吗？
Immunol Today. 1993 Jul;14(7):353-6. doi: 10.1016/0167-5699(93)90235-D.
2
Soluble interleukin-2 receptor and interleukin-2 in human amniotic fluid of normal and abnormal pregnancies.
Biol Neonate. 1993;63(5):281-4. doi: 10.1159/000243942.
3
Differential mRNA expression and production of interleukin-6 in placental trophoblast and villous core compartments.胎盘滋养层和绒毛核心区室中白细胞介素-6的mRNA差异表达及产生
Am J Reprod Immunol. 1993 Sep-Oct;30(2-3):131-5. doi: 10.1111/j.1600-0897.1993.tb00613.x.
4
A comparative study of the diagnostic performance of amniotic fluid glucose, white blood cell count, interleukin-6, and gram stain in the detection of microbial invasion in patients with preterm premature rupture of membranes.羊水葡萄糖、白细胞计数、白细胞介素-6及革兰氏染色对胎膜早破患者微生物入侵检测诊断性能的比较研究
Am J Obstet Gynecol. 1993 Oct;169(4):839-51. doi: 10.1016/0002-9378(93)90014-a.
5
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.用于细胞生长和存活的快速比色测定法：应用于增殖和细胞毒性测定。
J Immunol Methods. 1983 Dec 16;65(1-2):55-63. doi: 10.1016/0022-1759(83)90303-4.
6
Regulation of colony-stimulating factor 1 during pregnancy.孕期集落刺激因子1的调控
J Exp Med. 1986 Sep 1;164(3):956-61. doi: 10.1084/jem.164.3.956.
7
Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line.在一株依赖白细胞介素3的髓性白血病细胞系中，通过逆转录病毒整合导致c-myb基因截短。
Proc Natl Acad Sci U S A. 1986 Jul;83(14):5010-4. doi: 10.1073/pnas.83.14.5010.
8
Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis.硫酸乙酰肝素结合生长因子：一种基质细胞介导造血作用的机制。
Nature. 1988 Mar 24;332(6162):376-8. doi: 10.1038/332376a0.
9
Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.一种对B细胞杂交瘤具有生长因子活性的T细胞衍生淋巴因子的纯化及氨基末端氨基酸序列分析
Proc Natl Acad Sci U S A. 1986 Dec;83(24):9679-83. doi: 10.1073/pnas.83.24.9679.
10
Accumulation of colony-stimulating factor 1 in amniotic fluid during human pregnancy.人妊娠期间羊水内集落刺激因子1的蓄积
Am J Obstet Gynecol. 1989 Mar;160(3):655-6. doi: 10.1016/s0002-9378(89)80051-1.