Castro R R, Brant C Q, Ferreira L E, Geocze S, Ferrari Júnior A P, Lanzoni V P, Forones N M
Enfermaria de Gastroenterologia, Hospital São Paulo.
Arq Gastroenterol. 1994 Oct-Dec;31(4):145-8.
Peutz-Jeghers syndrome is a rare disease, characterized by autosomic inheritance, presenting skin stain and hamartomatous polyps. We report one case of Peutz-Jeghers syndrome and duodenal adenocarcinoma in a young male who presented with liver metastasis and pancreatic invasion. Such association is reported to be presented in 5% of patients with the syndrome. The reasons of such association are unknown, being possible that: 1) there is malignant degeneration of a adenomatous polyp; 2) malignant degeneration of a hamartomatous polyp, or 3) adenomatous portion of a hamartomatous polyp could undergo malignant transformation.
