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足月胎儿宫内生长受限的决定因素:沙特阿拉伯的经验

Determinants of term intrauterine growth retardation: the Saudi experience.

作者信息

al-Eissa Y A, Ba'Aqeel H S, Haque K N, AboBakr A M, al-Kharfy T M, Khashoggi T Y, al-Husain M A

机构信息

Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Am J Perinatol. 1995 Jul;12(4):278-81. doi: 10.1055/s-2007-994474.

DOI:10.1055/s-2007-994474
PMID:7575836
Abstract

In a clinical study from an unselected Saudi obstetric population, the incidence of and risk factors for intrauterine growth retardation among live births were investigated. From a total study group of 4578 consecutive live births, 76 (1.7%) infants were found to be growth retarded. These infants were then compared with a randomly selected control group of 76 term newborns with appropriate birthweight for their gestational ages. Delivery at term of a growth-retarded infant was significantly associated with maternal age under 20 years, maternal body mass index less than 23, first degree consanguinity, poor housing, primiparity, and inadequate prenatal care in univariate analysis. When considered jointly in multivariate logistic regression analysis, the significant determinants were reduced to primiparity, first degree consanguinity, and poor housing. These risk factors correctly predicted 63% and 71% of the intrauterine growth-retarded infants or normal birthweight infants, respectively.

摘要

在一项针对未经过筛选的沙特产科人群的临床研究中,调查了活产儿中宫内生长受限的发生率及危险因素。在总共4578例连续活产儿的研究组中,发现76例(1.7%)婴儿生长发育迟缓。然后将这些婴儿与随机选取的76例足月新生儿组成的对照组进行比较,这些对照组新生儿的出生体重与其孕周相称。在单因素分析中,生长发育迟缓婴儿的足月分娩与母亲年龄小于20岁、母亲体重指数小于23、一级近亲结婚、住房条件差、初产以及产前护理不足显著相关。在多因素逻辑回归分析中综合考虑时,显著的决定因素减少为初产、一级近亲结婚和住房条件差。这些危险因素分别正确预测了63%的宫内生长发育迟缓婴儿和71%的出生体重正常婴儿。

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