Stamp G E, Williams A S, Crowther C A
Birth. 1995 Sep;22(3):138-43. doi: 10.1111/j.1523-536x.1995.tb00689.x.
This randomized, controlled trial tested the hypothesis that women identified as more vulnerable to developing postnatal depression who attended two specific antenatal groups and one postnatal group have a reduced frequency of postnatal depression from 37 to 15 percent at 6 weeks, 12 weeks, and 6 months postpartum. A modified antenatal screening questionnaire was completed, and women identified as more vulnerable to postnatal depression were stratified by parity and randomly allocated to receive extra support groups or to a control group. The Edinburgh Postnatal Depression Scale (EPDS) was used to detect postnatal depression. Attendance at the support groups was low, 31 percent overall. At six weeks, in the intervention group, 8 (13%) of 64 women scored high (> 12) on the EPDS, compared with 11 (17%) controls. Similarly, at 12 weeks 7 (11%) of 63 versus 10 (15%) of 65 women scored higher than 12, and at 6 months, 9 (15%) of 60 versus 6 (10%) of 64 women scored higher than 12, indicating that the intervention did not reduce postnatal depression. It is possible that the method of applying the intervention, using groups separate from the standard antenatal classes, may have affected attendance. More research is required into ways of reaching and supporting women who may become depressed.
被确定为更易患产后抑郁症的女性参加两个特定的产前组和一个产后组后，产后6周、12周和6个月时产后抑郁症的发生率从37%降至15%。完成了一份改良的产前筛查问卷，被确定为更易患产后抑郁症的女性按产次分层，并随机分配接受额外的支持组或对照组。使用爱丁堡产后抑郁量表（EPDS）来检测产后抑郁症。支持组的参与率较低，总体为31%。在六周时，干预组64名女性中有8名（13%）在EPDS上得分较高（>12），而对照组为11名（17%）。同样，在12周时，63名女性中有7名（11%）得分高于12，而65名女性中有10名（15%）得分高于12；在6个月时，60名女性中有9名（15%）得分高于12，而64名女性中有6名（10%）得分高于12，这表明干预并未降低产后抑郁症的发生率。应用干预措施的方法，即使用与标准产前课程分开的小组，可能影响了参与率。需要对接触和支持可能患抑郁症的女性的方法进行更多研究。
