Leno C, Berciano J, Combarros O, Sedano C, Alvarez C, Merino J, Quintana F, Martín-Durán R, Rebollo M, Pascual J
Service of Neurology, University Hospital Marqués de Valdecilla, Faculty of Medicine, Santander, Spain.
Neurologia. 1995 Aug-Sep;10(7):283-7.
The aim of this prospective study was to determine the etiologic factors leading to stroke in a group of young adults. We studied 95 patients aged 50 years or under who were admitted with the diagnosis of stroke over a 2-year period. These patients underwent complete clinical and laboratory assessment for stroke. The etiology was established in 73 (76.8%) out of 95 cases. Arterial hypertension, embolism and atherosclerosis were found to be the most frequent causes in patients with ischemic stroke, whereas hypertension and aneurysm rupture were the most prevailing etiologies in patients with hemorrhagic stroke. Miscellaneous causes represented one fourth of all cases of the series. Coagulation abnormalities occurred in some patients, but in these cases there were also other well established causes. Paradoxical embolism was not observed. This study corroborates the importance of thorough diagnostic evaluation to establish an accurate diagnosis.
这项前瞻性研究的目的是确定一组年轻成年人中导致中风的病因。我们研究了95名年龄在50岁及以下、在两年期间因中风诊断入院的患者。这些患者接受了中风的全面临床和实验室评估。95例病例中有73例（76.8%）确定了病因。动脉高血压、栓塞和动脉粥样硬化被发现是缺血性中风患者最常见的病因，而高血压和动脉瘤破裂是出血性中风患者最主要的病因。其他各种病因占该系列所有病例的四分之一。一些患者出现凝血异常，但在这些病例中也存在其他明确的病因。未观察到反常栓塞。本研究证实了进行全面诊断评估以建立准确诊断的重要性。
