干扰素或丙型肝炎病毒诱发的自身免疫性再生障碍性贫血和严重血小板减少症？一例报告。
Interferon or hepatitis C virus induced autoimmune aplastic anemia and severe thrombocytopenia? A case report.
作者信息
Siciliano R, Trovato B A, Seminara G, Giustolisi V, Malaguarnera M
机构信息
Istituto di Medicina Interna e Geriatria, Università degli Studi di Catania.
出版信息
Ann Ital Med Int. 1995 Jul-Sep;10(3):193-4.
PMID:7577317
Abstract
We describe a case of aplastic anemia with severe thrombocytopenia in a patient affected by chronic active hepatitis C treated with interferon. The hematologic alterations did not disappear after suspension of interferon or after the ensuing steroid treatment. Administration of cyclosporin markedly improved the hematologic parameters and serum transaminase levels.
摘要
我们描述了一例患有慢性丙型活动性肝炎且接受干扰素治疗的再生障碍性贫血伴严重血小板减少症的患者。在停用干扰素或随后进行类固醇治疗后，血液学改变并未消失。给予环孢素显著改善了血液学参数和血清转氨酶水平。
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